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Gal Bitan, PhD

Gal Bitan, PhD

[CONTACT INFORMATION]
David Geffen School of Medicine at UCLA
635 Charles E. Young Drive South/NRB 451
Los Angeles, CA 90095
Phone: (310) 206-2082
Fax: (310) 206-1700
E-mail: gbitan@mednet.ucla.edu

[AFFILIATION]
Assistant Professor, Department of Neurology

[EDUCATION & CERTIFICATIONS]
Bachelors of Science, The Hebrew University of Jerusalem, Israel, 1985 – 1988
Masters of Science, The Hebrew University of Jerusalem, Israel, 1988 – 1989
PhD, The Hebrew University of Jerusalem, Israel, 1990 – 1996
Postdoc, Clark University, Worcester, MA and Beth Israel Deaconess Medical Center/Harvard Medical School, Boston, MA, 1996 – 1999
Postdoc, Brigham and Women's Hospital/Harvard Medical School, Boston, MA, 1999 – 2002

[RESEARCH INTERESTS]
The Bitan laboratory focuses on developing new therapeutic and diagnostic tools for diseases related to protein misfolding and aggregation, particularly Alzheimer's and Parkinson's diseases. The laboratory synthesizes novel molecules and explores their potential for diagnostic and therapeutic uses. These efforts are guided by structural knowledge that is obtained though multifaceted, collaborative experimental and theoretical studies. The techniques and methodologies used in the laboratory are interdisciplinary in nature, ranging from peptide chemistry, through biochemistry and biophysics, to molecular, cell, and animal biology.

[SELECT PUBLICATIONS]
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[PRINCIPAL INVESTIGATOR NIH GRANTS]
Development of Amyloid B-Protein Oligomerization Inhibitors

[OTHER GRANTS]
California Department of Public Health — Novel Reagents for Alzheimer's Disease Diagnostics. (07-65798; PI: Bitan)

United States-Israel Binational Science Foundation — The Effect of Inhibitors and Modulators on Amyloid β-protein Assembly and Toxicity: A Mechanistic Investigation. (2007187; Co-PI: Bitan and Sagi)

RJG Foundation — Examination of Small-Molecule Inhibitors of α-synuclein in An Animal Model of Parkinson's Disease. (PI: Bitan)

[LINKS]
Shanmugam A, Monien BH, and Bitan G. Development in Diagnostic and Therapeutic Strategies for Alzheimer's Disease. Research Progress in Alzheimer's Disease and Dementia. 2008; 3: 193-250.

Li H, Rahimi F, Sinha S, Maiti P, Murakami K, and Bitan G. Amyloids and Protein Aggregation—Analytical Methods. Encyclopedia Anal. Chem. 2009; Published online, DOI: 10.1002/9780470027318.a9038